Tetrapyrroles and derivatives
Frontier Specialty Chemicals 5g meso-Tetra(pentafluorophenyl)porphine chlorin free, 25440-14-6 MFCD00010032
meso-Tetra(pentafluorophenyl)porphine chlorin free5,10,15,20-Tetrakis(pentafluorophenyl)-21H,23H-porphine CAS: 25440-14-6 MFCD00010032 Porphyrins Synthetic Porphyrins
Medchemexpress LLC Protoporphyrin IX (disodium) | 50865-01-5 | 96.5% | 25 MG
Protoporphyrin IX disodium is a final intermediate in the heme biosynthetic pathway. It acts as a radiation sensitizer, enhancing ROS generation even in hypoxic conditions and inducing DNA damage. It also functions as a photosensitizer, undergoing photobleaching through direct degradation by light irradiation. This product is promising for research of sonodynamic and photodynamic agents for various cancers, including bladder cancer and nodular basal cell carcinoma.
- Final intermediate in the heme biosynthetic pathway
- Acts as a radiation sensitizer
- Enhances ROS generation and induces DNA damage
- Functions as a photosensitizer
- Undergoes photobleaching by light irradiation
- Accumulates in tumor cells after 5-aminolevulinic acid administration
- Causes selective improvement of basal cell carcinoma
- Promising for research into sonodynamic and photodynamic agents for various cancers
Frontier Specialty Chemicals 5g meso-Tetra(4-carboxyphenyl)porphine, 14609-54-2 MFCD00064860
meso-Tetra(4-carboxyphenyl)porphinemeso-Tetraphenylporphine- 4,4',4'',4'''-tetracarboxylic acid CAS: 14609-54-2 MFCD00064860 Porphyrins Synthetic Porphyrins
Frontier Specialty Chemicals 10g meso-Tetra(4-pyridyl)porphine, 16834-13-2 MFCD00009626
meso-Tetra(4-pyridyl)porphine5,10,15,20-Tetra(4-pyridyl)-21H,23H-porphine CAS: 16834-13-2 MFCD00009626 Porphyrins Synthetic Porphyrins
eMolecules 14643-66-4 | Medchem Express | Coproporphyrin III | 1mg | 446256752 | HY-101398 | 654.72 | C36H38N4O8
Ambeed | (9-Oxo-9H-fluoren-2-yl)boronic acid | 250mg | 721299020 | A1618029 | 2036064-15-8 | 224.020 | C13H9BO3
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Enzo Life Sciences Protoporphyrin IX (free acid) (300mg). CAS: 553-12-8
Protoporphyrin IX free acid, as distinct from its zinc salt (which inhibits heme oxygenase), activates soluble guanylyl cyclase (sGC) by binding directly to the enzyme. A useful reagent in cases where the use of nitric oxide (NO) or nitric oxide donors is undesirable. Alternative name: 8,13-Divinyl-3,7,12,17-tetramethyl-21H,23H-porphine-2,18-dipropionic acid. Purity: ≥95% (HPLC). Solubility: Dissolve initially in 0.1M base (Tris base or NaOH), then add water miscible organic solvent (EtOH (10mg/ml), MeOH, DMSO (10mg/ml), DMF) until solution is 50/50 base/solvent. When a clear solution is obtained, it can be diluted into an aqueous medium and titrated or buffered to any pH>7. Use immediately. Long Term Storage: -20°C.
eMolecules 19444-84-9 | Ambeed | 3-Hydroxydihydrofuran-2(3H)-one | 1g | 525145111 | A237190 | MFCD00134268 | 102.089 | C4H6O3
Medchem Express | (Z)-Thiothixene | 5mg | 446259291 | HY-108324 | 3313-26-6 | MFCD00079574 | 443.620 | C23H29N3O2S2
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Cayman Chemical Mn III ProtoporphyrIn IX Chl
A metalloporphyrin; induces mRNA expression of the genes encoding δ-aminolevulinate synthase and HO in chick embryo liver cells at 10 µM; manganese(III) protoporphyrin IX chloride-containing nanobialys have been used in MRI of fibrin clots in vitro; has been used in the synthesis of MnGGH
Cayman Chemical ZInc ProtoporphyrIn-9 100mg
A competitive inhibitor of heme oxygenase that also inhibits soluble guanylyl cyclase and inactivates the NOS isoforms nNOS, iNOS, and eNOS (IC50s = 0.8, 4, and 5 μM, respectively); used to assess iron status and to diagnose iron disorders and has shown therapeutic potential in hyperbilirubinemia
Selleck Chemical LLC Protoporphyrin IX (PPIX) S5145-25mg
Protoporphyrin IX (PPIX) is a heterocyclic organic compound which consists of four pyrrole rings and is the final intermediate in the heme biosynthetic pathway
Medchemexpress LLC Zinc protoporphyrin (Zn(II)-protoporphyrin IX) | 15442-64-5 | 99.9% | 626.02 g/mol | C34H32N4O4Zn | 1 ML
Zinc protoporphyrin (Zn(II)-protoporphyrin IX) is a research reagent that acts as a competitive heme oxygenase-1 (HO-1) inhibitor and a biomarker for iron-deficiency screening. It is supplied as a ready-to-use 10 mM solution in DMSO and as solid preparations for laboratory use. Typical applications include cellular assays, mechanistic studies, and in vivo screening.
- Ready-to-use 10 mM solution in DMSO.
- Also available as solid in multiple mass sizes.
- Competitive heme oxygenase-1 (HO-1) inhibitor for research.
- Used as a screening marker for iron deficiency in vivo.
- High purity (approximately 99.9%).
- Molecular weight 626.02 g/mol; formula C34H32N4O4Zn.
- Includes product data sheet and SDS for handling information.
![eMolecules 71216-20-1 | 2(3H)-Benzothiazolethione, 5-bromo- | Combi-Blocks, Inc. | MFCD01569939 | 246.140 | C7H4BrNS2 | 95.000 | Brc1ccc2sc(=S)[nH]c2c1 | 1g | 603140428](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502187689.JPG-250.jpg)
eMolecules 71216-20-1 | 2(3H)-Benzothiazolethione, 5-bromo- | Combi-Blocks, Inc. | MFCD01569939 | 246.140 | C7H4BrNS2 | 95.000 | Brc1ccc2sc(=S)[nH]c2c1 | 1g | 603140428
2(3H)-Benzothiazolethione, 5-bromo- | Combi-Blocks, Inc. | 71216-20-1 | MFCD01569939 | 246.140 | C7H4BrNS2 | 95.000 | Brc1ccc2sc(=S)[nH]c2c1 | 1g | 603140428
Medchemexpress LLC Protoporphyrin IX | 553-12-8 | MFCD00078028 | ≥98.0% | 100 MG
Protoporphyrin IX is a final intermediate in the heme biosynthetic pathway, which acts as a radiation sensitizer enhancing ROS generation even in a hypoxic state and inducing DNA damage. It also functions as a photosensitizer, undergoing photobleaching through direct degradation by light irradiation. It accumulates following 5-aminolevulinic acid (5-ALA) administration in rat tumor cells. When activated by red fluorescence at a peak wavelength of 405 nm, Protoporphyrin IX selectively improves basal cell carcinoma. It shows promise as a sonodynamic and photodynamic agent for various cancers, including bladder cancer and nodular basal cell carcinoma.
- Acts as a radiation sensitizer enhancing ROS generation.
- Induces DNA damage.
- Acts as a photo sensitizer.
- Promising for research of sonodynamic and photodynamic agents for a wide range of cancers.
eMolecules 42417-39-0 | 3-Aminodihydrofuran-2(3H)-one hydrochloride | MFCD27977179 | 1g
Ambeed | 5-Ethoxy-1H-indole-2-carboxylic acid | 250mg | 632809689 | A591873 | 93476-60-9 | MFCD02664445 | 205.213 | C11H11NO3
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